Healthcare emerges as an industry experiencing dramatic changes because technology takes hold throughout the sector. Through software, healthcare providers execute process optimisations that enhance patient care while maintaining regulatory standards. Healthcare software now comprehensively supports the health ecosystem through its improvements in clinical operational efficiency and its growth in data operations and patient experience development.
According to Statista’s report for 2026, the healthcare IT market in the United States has grown to over $70 billion because health technology investments continue to rise while the need for digital healthcare solutions expands. The healthcare landscape adds momentum to this trend because of regulatory changes, telemedicine advancements, electronic health record implementation, and artificial intelligence developments.
Healthcare Software Companies in the USA lead this revolution by providing healthcare systems with tools to develop modern operational capabilities.
What role does healthcare software play in revolutionising U.S. healthcare systems?
- Data Management: Parent data is handled securely through efficient methods by healthcare software systems, including advanced EMR systems.
- Regulatory Compliance: Healthcare organisations achieve regulatory compliance, such as HIPAA, through software systems.
- Clinical Efficiency: The optimisation of medical workflows achieved through software produces safer healthcare delivery while boosting efficiency.
- Telemedicine: Healthcare software continues to grow as a leading segment in the industry through its ability to provide video consultation services and remote patient monitoring.
- Patient Engagement: The software gives patients improved access to tools that let them manage their schedules, track their health status, and view their test results.
- Revenue Cycle Management: Healthcare organisations benefit from software that optimises their workflow for billing functions, insurance claims procedures, and coding tasks.
- Interoperability: Today’s advanced software systems create smooth interoperable connections between various healthcare IT platforms.
- Artificial Intelligence: AI-powered software transforms medical diagnostics through data-driven decision systems while creating patient-specific care approaches.
The Impact of Healthcare Software on the US Healthcare System
- Improved Clinical Decision-Making: Through real-time data access, healthcare software helps doctors make diagnostic evaluations and generate individual treatment plans.
- Enhanced Patient Outcomes: Software platforms that use data-driven care help healthcare providers monitor patients and achieve better long-term health results.
- Administrative Efficiency: Automating regular administrative activities, including scheduling, billing, and documentation functions, decreases operational expenses while eliminating administrative responsibilities.
- Support for Value-Based Care: Software applications assist providers in transitioning their operational models from quantity-based billing systems to quality-focused and cost-efficient value-based care delivery.
- Chronic Disease Management: Chronic illness management platforms enable constant disease monitoring and better strategies to improve long-term patient outcomes.
- Data Interoperability: When health data can move freely between connected systems, it enables continuous care delivery and provider collaboration.
- Rapid Adoption of New Technologies: Healthcare operations today more frequently incorporate cloud-based systems, AI tools, and mobile applications.
- Patient-Centric Services: Software makes healthcare more patient-centric by providing accessible portals, remote consultations, and personalised care tools.
Top 10 Healthcare Software Companies in the USA
1. Epic Systems Corporation

Operating as a leading healthcare IT company in the US market and one of the top IT companies in the world, Epic Systems delivers end-to-end EHR and healthcare management software solutions to customers. Their software provides healthcare providers with tools for patient record management, clinical workflow enhancement, and treatment quality improvement.
Key Features:
- Fully integrated EHR system
- Mobile health applications
- Health information becomes accessible through the patient portal system.
- Clinical decision support tools
- Revenue cycle management
- Data analytics and reporting tools
Services:
- EHR implementation and support
- Telemedicine integration
- Clinical data management
- Healthcare employees require training and ongoing assistance as part of their system implementation.
2. Oracle Health

Healthcare software leader Oracle Health delivers users EHR and health information technology solutions. Integrating patient data enables healthcare providers to achieve better outcomes by supporting instant decision-making processes.
Key Features:
- Cloud-based EHR solutions
- Patient engagement tools
- Population health management
- Interoperability with other systems
- Analytics and reporting capabilities
- Clinical documentation and workflow management
Services:
- EHR and practice management
- Cloud-based health information systems
- Clinical decision support tools
- Patient portal services
3. Veradigm

As a leading healthcare technology company, Veradigm develops innovative solutions that unite payers with providers and life sciences to produce better patient results at reduced healthcare costs. The Allscripts’ former business unit, Veradigm, delivers many health IT solutions through its electronic health records (EHR) systems, data analytics tools, and patient engagement platforms. This healthcare system gives its professionals decision-making capabilities through insight generation and supports effortless information exchange between healthcare organisations.
Key Features:
- The EHR systems integrate their features for medical record management.
- The solution delivers both practice management solutions and revenue cycle management capabilities.
- The life sciences field uses real-world evidence as an essential component for generating information.
- Data-driven clinical decision support tools
- Interoperability across providers and payers
- Cloud-based infrastructure and scalable platforms
- The healthcare sector uses enhanced analytic systems to manage population health effectively.
Services:
- Ambulatory practices benefit from combined EHR systems and practice management functionalities.
- Healthcare stakeholders obtain data analytics along with actionable insights through our platform.
- The tools enable collaboration between the payer industry alongside life sciences entities.
- Patient engagement platforms
- The system also includes Revenue cycle and financial management solutions.
- Interoperability and data integration services
4. Medtronic

The medical device manufacturing corporation Medtronic operates healthcare software solutions that integrate medical device data to emphasise chronic condition management. Their software platforms serve both disease management requirements and clinical decision processes.
Key Features:
- Device integration and monitoring
- Chronic disease management
- Data analytics and reporting tools
- Remote patient monitoring
- Clinical decision support
- Mobile health applications
Services:
- Medical device integration
- Patient monitoring and management
- Chronic disease management
- Telemedicine solutions
5. McKesson

McKesson is a significant healthcare IT services manager that develops extensive applications, including supply chain solutions, EHR systems, and pharmacy operational tools. McKesson delivers solutions designed to make healthcare operations more efficient while maintaining regulatory compliance standards through its platforms.
Key Features:
- EHR and practice management software
- Pharmacy management systems
- Data analytics tools
- Cloud-based solutions
- Medication management and tracking
- Supply chain management tools
Services:
- EHR solutions
- Supply chain and pharmacy management
- Health data analytics
- Integration with healthcare systems
6. Athenahealth

The main reason people know about Athenahealth is its cloud-based EHR and practice management software solutions. These solutions give healthcare providers tools to organise medical records, make appointment schedules, and process payments more efficiently.
Key Features:
- Cloud-based EHR system
- Patient scheduling and appointment management
- Revenue cycle management
- Medical billing and coding
- Analytics and reporting
- Patient portal integration
Services:
- EHR and practice management software
- Billing and coding services
- Revenue cycle management
- Population health management
7. NextGen Healthcare

As part of its service offering, NextGen Healthcare delivers three main business solutions: EHR, practice management, and revenue cycle management. Healthcare delivery optimisation forms the core of its software products, alongside enhanced efficiency in medical practices.
Key Features:
- Integrated EHR and practice management
- Cloud-based solutions
- Billing and claims management
- Patient engagement tools
- Data analytics and reporting
- Clinical decision support
Services:
- EHR and practice management
- Revenue cycle management
- Patient engagement solutions
- Telehealth solutions
8. Greenway Health

Greenway Health delivers healthcare practice software solutions that include EHR, practice management and revenue cycle management functions. Their software solutions work toward better healthcare delivery, workflow optimisation, and patient satisfaction.
Key Features:
- EHR and practice management
- Cloud-based solutions
- Revenue cycle management
- Appointment scheduling tools
- Patient engagement and portal
- Data analytics and reporting
Services:
- EHR implementation and support
- Revenue cycle management
- Telemedicine solutions
- Analytics and reporting services
9. Optum

Description: As a health services and technology company, Optum provides healthcare IT solutions through its platform, offering analytics, management and decision support software capabilities. The platforms from this healthcare technology company help organisations make better clinical and operational decisions.
Key Features:
- Healthcare analytics and insights
- Data management and reporting
- Patient engagement tools
- EHR and practice management integration
- Artificial intelligence and machine learning
- Value-based care solutions
Services:
- Healthcare analytics
- EHR and practice management solutions
- Value-based care optimisation
- Revenue cycle management
10. eClinicalWorks

eClinicalWorks’ healthcare software solutions feature EHR systems, practice management capabilities, and population health solutions. Through their technology platform, physicians can optimise workflows while enhancing clinical results and better controlling patient population management.
Key Features:
- EHR and practice management
- Population health management
- Telemedicine solutions
- Patient engagement tools
- Analytics and reporting
- Clinical decision support
Services:
- EHR implementation and support
- Telemedicine solutions
- Population health management
- Data analytics and reporting
Conclusion
Healthcare Software Companies in the USA function as essential collaborators rather than traditional technology vendors, leading modern healthcare delivery into the digital age. EHR systems, along with AI-driven analytics, serve as enabling tools that provide clinicians with medical capabilities and operational advantages to enhance patient treatment and health processes across clinical areas. Healthcare software will be the backbone of American healthcare’s future development as value-based care, digital patient engagement, and interoperability gain momentum.
FAQs
1. Is Veradigm a U.S.-based company?
Veradigm operates as a United States-based organisation from its headquarters.
2. Where does the United States position its leading healthcare software company?
Epic Systems is the leading provider of electronic health records and healthcare technology solutions in the healthcare industry.
3. What improvements does AI technology bring to healthcare software?
AI technology delivers diagnostic enhancements and outcome predictions while creating personalised treatment protocols.
4. Are cloud-based healthcare platforms secure?
Healthcare platforms that protect patient data use encryption technologies and adhere to HIPAA standards.